Comparison
Selank vs Semax
Two Russian-developed nootropic peptides
The key difference
Selank is based on tuftsin, an immune peptide, and is studied mainly for anxiety. Semax is based on a fragment of ACTH and is studied mainly for cognition and brain recovery.
| Selank | Semax | |
|---|---|---|
| Class | Synthetic tuftsin analog | Synthetic ACTH fragment analog |
| Evidence | Early human research | Early human research |
| Status | Not FDA-approved. | Not FDA-approved. |
| Also known as | — | — |
| Researched for | Cognition & mood | Cognition & mood |
| Evidence strength | Early human research | Early human research |
What else differs
- Both are registered medicines in Russia, where most of their research was done.
- Independent Western clinical trials are limited for both, and neither is FDA-approved.
Bottom line
Related origins, different focus areas, and a similar evidence gap outside Russia.
Read the research
Selank on PubMed →
Semax on PubMed →
Educational content, not medical advice. This page does not recommend or dose any substance. Compounds that are not FDA-approved have not been established as safe or effective in people.